Original Articles 2001

  1. Ueki, M., Teruya, T., Nie, L., Usami, R., Yoshida, M., and Osada, H.
    A new trichostatin derivative,trichostain RK, from Strepromyces sp. RK98-A74.
    J. Antibiot., 54, 1093-1095 (2001) PubMed

  2. Sodeoka, M., Sampe, R., Kojima, S., Baba, Y., Usui, T., Ueda, K., and Osada, H.
    Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition.
    J. Med. Chem., 44,3216-3222 (2001) PubMed

  3. Nie, L., Ueki, M., Kakeya, H., and Osada, H.
    A facile and effective screening method for p21"WAF1" promoter activators from microbial metabolites.
    J. Antibiot., 54, 783-788 (2001) PubMed

  4. Kakeya, H., Kageyama, S., Nie, L., Onose, R., Okada, G., Beppu, T., Norbury, CJ., and Osada, H.
    Lucilactaene,a new cell cycle inhibitor in p53-transfected cancer cells, produced by a Fusarium sp.
    J. Antibiot., 54, 850-854 (2001) PubMed

  5. Hamaguchi, T., Takahashi, A., Manaka, A., Sato, M., and Osada, H.
    TU-572, a potent and selective CD45 inhibitor, suppresses anaphylaxis and murine hypersensitivity reaction.
    Int. Arch. Allergy lmmunol., 126, 318-324 (2001) PubMed

  6. Usui, T., Kojima, S., Kidokoro, S., Ueda, K., Osada, H., and Sodeoka, M.
    Design and synthesis of a dimeric derivative of RK-682 with increased inhibitory activity against VHR, a dual-specificity ERK phosphatase implications for the molecular mechanism of the inhibition.
    Chem. Biol., 8, 1209-1220 (2001) PubMed

  7. Sano, T., Usui, T., Ueda, K., Osada, H., and Kaya, K.
    Isolation of new protein phosphatase inhibitors from two Cyanobacteria species, Planktothrix spp.
    J. Nat. Prod., 64, 1052-1055 (2001) PubMed

  8. Togashi, K., Ko, H-R., Ahn, J-S., and Osada, H.
    Inhibition of telomerase activity by fungus metabolites, CRM646-A and thielavin B.
    Biosci. Biotechnol. Biochem., 65, 651-653 (2001) PubMed