Original Articles 2009

  1. Ueki, M., Suzuki, R., Takamatsu, S., Takagi, H., Uramoto, M., Ikeda,H., and Osada, H.
    Nocardamin production by Streptomyces avermitilis.
    Actinomycetol, 23, 34-39 (2009)

  2. Hashimoto, M., Higuchi, Y., Takahashi, S., Osada, H., Sakaki, T., Toyomasu, T., Sassa, T., Kato, N., and Dairi, T.
    Functional analyses of P450 genes responsible for the early steps of brassicicene C biosynthesis.
    Bioorg Med Chem Lett, 19, 5640-5643 (2009) PubMed

  3. Kawai, K., Saito, A., Sudo, T., and Osada, H.
    A p38 mitogen-activated protein kinase inhibitor screening method using growth recovery of Escherichia coli as an index.
    Anal Biochem, 388, 128-133 (2009) PubMed

  4. Li, W., Luo, Y., Ju, J., Rajski, S., Osada, H., and Shen, B.
    Characterization of the tautomycetin biosynthetic gene cluster from streptomyces griseochromogenes provides new insight into dialkylmaleic anhydride biosynthesis.
    J Nat Prod, 72, 450 (2009) PubMed

  5. Na, M., Yeon Kim, B., Osada, H., and Seog Ahn, J.
    Inhibition of protein tyrosine phosphatase 1B by lupeol and lupenone isolated from Sorbus commixta.
    J Enzyme Inhib Med Chem, 24, 1056-1059 (2009) PubMed

  6. Nishida, H., Motoyama, T., Yamamoto, S., Aburatani, H., and Osada, H.
    Genome-wide maps of mono- and di-nucleosomes of Aspergillus fumigatus.
    Bioinformatics, 25, 2295-2297 (2009) PubMed

  7. Fukuda, I., Ito, A., Uramoto, M., Saitoh, H., Kawasaki, H., Osada, H., and Yoshida, M.
    Kerriamycin B inhibits protein SUMOylation.
    J. Antibiot. 62, 221-224 (2009) PubMed

  8. Ju, J., Li, W., Yuan, Q., Peters, N.R., Hoffmann, F.M., Rajski, S.R., Osada, H., and Shen, B.
    Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity.
    Org. Lett. 11, 1639-1642 (2009) PubMed

  9. He, L., Kim, S., Kwon, O., Jeong, S., Kim, M., Lee, H., Osada, H., Jung, M., Ahn, J., and Kim, B. “
    ATM blocks tunicamycin-induced endoplasmic reticulum stress.”
    FEBS Lett. 583, 903-908 (2009) PubMed

  10. Simizu, S., Teruya, T., Nogawa, T., Aono, H., Ueki, M., Uramoto, M., Kobayashi, Y., and Osada, H.
    Deamino-hydroxy-phoslactomycin B, a biosynthetic precursor of phoslactomycin, induces myeloid differentiation in HL-60 cells..
    Biochem. Biophys. Res. Commun., 383, 406-410 (2009) PubMed

  11. Kato, N., Suzuki, H., Takagi, H., Asami, Y., Kakeya, H., Uramoto, M., Usui, T., Takahashi, S., Sugimoto, Y., and Osada, H.
    Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.
    Chembiochem, 10, 920-928 (2009) PubMed

  12. Miyazaki, I., Simizu, S., Ishida, K., and Osada, H.
    On-chip fragment-based approach for discovery of high-affinity bivalent inhibitors.
    Chembiochem, 10, 838-843 (2009) PubMed

  13. Miyazaki, I., Okumura, H., Simizu, S., Takahashi, Y., Kanoh, N., Muraoka, Y., Nonomura, Y., and Osada, H.
    Structure-affinity relationship study of bleomycins and Shble protein by use of a chemical array.
    Chembiochem, 10, 845-852 (2009) PubMed

  14. Takagi, S., Simizu, S., and Osada, H.
    RECK negatively regulates matrix metalloproteinase-9 transcription.
    Cancer Res., 69, 1502-1508 (2009) PubMed

  15. Asami, Y., Mori, M., Koshino, H., Sekiyama, Y., Teruya, T., Simizu, S., Usui, T., and Osada, H.
    A cell-based screening to detect inhibitors of BRAF signaling pathway.
    J. Antibiot., 62, 105-107 (2009) PubMed

  16. Watanabe, N., Sekine, T., Takagi, M., Iwasaki, J., Imamoto, N., Kawasaki, H., and Osada, H.
    Deficiency in chromosome congression by the inhibition of Plk1 polo box domain-dependent recognition.
    J. Biol. Chem., 284, 2344-2353 (2009) PubMed

  17. Tamura, Y., Simizu, S., Muroi, M., Takagi, S., Kawatani, M., Watanabe, N., and Osada, H.
    Polo-like kinase 1 phosphorylates and regulates Bcl-xL during pironetin-induced apoptosis.
    Oncogene, 28, 107-116 (2009) PubMed

  18. Tazawa, H., Fujita, C., Machida, K., Osada, H., and Ohta, Y.
    Involvement of cyclophilin D in mitochondrial permeability transition induction in intact cells.
    Arch. Biochem. Biophys., 481, 59-64 (2009) PubMed