Original Articles 2013

  1. Futamura Y, Kawatani M, Muroi M, Aono H, Nogawa T, Osada H.: Identification of a molecular target of a novel fungal metabolite, pyrrolizilactone, by phenotypic profiling systems.
    Chembiochem, 14 (18): 2456-2463 (2013) PubMed [ doi: 10.1002/cbic.201300499 ]
  2. Hirohama M, Kumar A, Fukuda I, Matsuoka S, Igarashi Y, Saitoh H, Takagi M, Shin-Ya K, Honda K, Kondoh Y, Saito T, Nakao Y, Osada H, Zhang KY, Yoshida M, Ito A.: Spectomycin B1 as a Novel SUMOylation Inhibitor That Directly Binds to SUMO E2.
    ACS Chem Biol, 8 (12): 2635-2642 (2013) PubMed [ doi: 10.1021/cb400630z ]
  3. Nogawa T, Kawatani M, Uramoto M, Okano A, Aono H, Futamura Y, Koshino H, Takahashi S, Osada H.: Pyrrolizilactone, a new pyrrolizidinone metabolite produced by a fungus.
    J Antibiot, 66 (10): 621-623 (2013) PubMed [ doi: 10.1038/ja.2013.55 ]
  4. Nakajima Y, Kawamura T, Maeda K, Ichikawa H, Motoyama T, Kondoh Y, Saito T, Kobayashi T, Yoshida M, Osada H, Kimura M.: Identification and characterization of an inhibitor of trichothecene 3-O-acetyltransferase, TRI101, by the chemical array approach.
    Biosci Biotechnol Biochem, 77 (9): 1958-1960 (2013) PubMed [ doi: 10.1271/bbb.130153 ]
  5. Yabumoto T, Miyazawa K, Tabuchi M, Shoji S, Tanaka M, Kadota M, Yoshizako M, Kawatani M, Osada H, Maeda H, Goto S.: Stabilization of tooth movement by administration of reveromycin A to osteoprotegerin-deficient knockout mice.
    Am J Orthod Dentofacial Orthop, 144 (3): 368-380 (2013) PubMed [ doi: 10.1016/j.ajodo.2013.04.016 ]
  6. Ooi LC, Watanabe N, Futamura Y, Sulaiman SF, Darah I, Osada H.: Identification of small molecule inhibitors of p27Kip1 ubiquitination by high-throughput screening.
    Cancer Sci, 104 (11), 1461-1467 (2013) PubMed [ doi: 10.1111/cas.12246 ]
  7. Noguchi T, Oishi S, Honda K, Kondoh Y, Saito T, Kubo T, Kaneda M, Ohno H, Osada H, Fujii N.: Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors.
    Bioorg Med Chem Lett, 23 (13): 3802-3805 (2013) PubMed [ doi: 10.1016/j.bmcl.2013.04.094 ]
  8. Ueki M, Koshiro N, Aono H, Kawatani M, Uramoto M, Kawasaki H, Osada H.: Isolation of new polyketide metabolites, linearolides A and B, from Streptomyces sp. RK95-74.
    J Antibiot, 66 (6): 333-337 (2013) PubMed [ doi: 10.1038/ja.2013.19 ]
  9. Bekh-Ochir D, Shimada S, Yamagami A, Kanda S, Ogawa K, Nakazawa M, Matsui M, Sakuta M, Osada H, Asami T, Nakano T.: A novel mitochondrial DnaJ/Hsp40 family protein BIL2 promotes plant growth and resistance against environmental stress in brassinosteroid signaling.
    Planta, 237 (6): 1509-1525 (2013) PubMed [ doi: 10.1007/s00425-013-1859-3 ]
  10. Kato N., Suzuki H., Okumura H., Takahashi S., Osada H.:
    A point mutation in ftmD blocks the fumitremorgin biosynthetic pathway in Aspergillus fumigatus strain Af293
    Biosci Biotechnol Biochem, 77 (5): 1061-1067 (2013) PubMed [ doi: 10.1271/bbb.130026 ]
  11. Chinen T, Kazami S, Nagumo Y, Hayakawa I, Ikedo A, Takagi M, Yokosuka A, Imamoto N, Mimaki Y, Kigoshi H, Osada H, Usui T.: Glaziovianin A prevents endosome maturation via inhibiting microtubule dynamics.
    ACS Chem Biol, 8 (5): 884-889 (2013) PubMed [ doi: 10.1021/cb300641h ]
  12. Nogawa T, Takahashi S, Sekiyama Y, Takagi H, Uramoto M, Koshino H, Kawatani M, Shimizu T, Osada H.: Creation of novel reveromycin derivatives by alcohol-added fermentation.
    J Antibiot, 66 (4): 247-250 (2013) PubMed [ doi: 10.1038/ja.2012.115 ]
  13. Kanoh N, Suzuki T, Kawatani M, Katou Y, Osada H, Iwabuchi Y.: Dual structure-activity relationship of osteoclastogenesis inhibitor methyl gerfelin based on TEG scanning.
    Bioconjug Chem, 24 (1): 44-52 (2013) PubMed [ doi: 10.1021/bc3003666 ]
  14. Zimmermann TJ, Bürger M, Tashiro E, Kondoh Y, Martinez NE, Görmer K, Rosin-Steiner S, Shimizu T, Ozaki S, Mikoshiba K, Watanabe N, Hall D, Vetter IR, Osada H, Hedberg C, Waldmann H.:
    Boron-based inhibitors of acyl protein thioesterases 1 and 2.
    Chembiochem, 14 (1): 115-122 (2013) PubMed [ doi: 10.1002/cbic.201200571 ]