Original Articles 2018

  1. Otaka J, Shimizu T, Futamura Y, Hashizume D, Osada H.: Structures and synthesis of hitoyopodins: bioactive aromatic sesquiterpenoids produced by the mushroom Coprinopsis cinerea.
    Org Lett, [Epub ahead of print] (2018) PMID: 30234313 [ doi: 10.1021/acs.orglett.8b02788 ]
  2. Futamura Y, Muroi M, Aono H, Kawatani M, Hayashida M, Sekine T, Nogawa T, Osada H.: Bioenergetic and proteomic profiling to screen small molecule inhibitors that target cancer metabolisms.
    Biochim Biophys Acta, [Epub ahead of print] (2018) PMID: 29883687 [ doi: 10.1016/j.bbapap.2018.06.001 ]
  3. Nakano T, Tanaka S, Ohtani M, Yamagami A, Takeno S, Hara N, Mori A, Nakano A, Hirose S, Himuro Y, Kobayashi M, Kushiro T, Demura T, Asami T, Osada H, Shinozaki K.: FPX is a novel chemical inducer that promotes callus formation and shoot regeneration in plants.
    Plant Cell Physiol, 59(8): 1555-1567 (2018) PMID: 30053249 [ doi: 10.1093/pcp/pcy139 ]
  4. Jia ZJ, Takayama H, Futamura Y, Aono H, Bauer JO, Strohmann C, Antonchick AP, Osada H, Waldmann H.: Catalytic enantioselective synthesis of a pyrrolizidine-alkaloid-inspired compound collection with antiplasmodial activity.
    J Org Chem, 83(13): 7033–7041 (2018) PMID: 29460633 [ doi: 10.1021/acs.joc.7b03202 ]
  5. Kato N, Nogawa T, Takita R, Kinugasa K, Kanai M, Uchiyama M, Osada H, Takahashi S.: Control of the stereochemical course of [4+2] cycloaddition during trans-decalin formation by Fsa2-family enzymes.
    Angew Chem Int Ed Engl, 57(31): 9754-9758 (2018) PMID: 29972614 [ doi: 10.1002/anie.201805050 ]
  6. Jang JP, Han JM, Jung HJ, Osada H, Jang JH, Ahn JS.: Anti-angiogenesis effects induced by octaminomycins A and B against HUVECs.
    J Microbiol Biotechnol, [Epub ahead of print] (2018) PMID: 30021429 [ doi: 10.4014.jmb/1806.06046 ]
  7. Qi J, Cheng L, Sun Y, Hirata Y, Ushida N, Ma Z, Osada H, Nishikawa T, Xiang L.: Identification of an asexual reproduction inducer of phytopathogenic and toxigenic Fusarium.
    Angew Chem Int Ed Engl, 57(27): 8100-8104 (2018) PMID: 29729060 [ doi: 10.1002/anie.201803329 ]
  8. Maeda K, Ichikawa H, Nakajima Y, Motoyama T, Ohsato S, Kanamaru K, Kobayashi T, Nishiuchi T, Osada H, Kimura M.: Identification and characterization of small molecule compounds that modulate trichothecene production by Fusarium graminearum.
    ACS Chem Biol, 13(5): 1260-1269 (2018) PMID: 29565558 [ doi: 10.1021/acschembio.8b00044 ]
  9. Wilke J, Kawamura T, Watanabe N, Osada H, Ziegler S, Waldmann H.: Identification of cytotoxic, glutathione-reactive moieties inducing accumulation of reactive oxygen species via glutathione depletion.
    Bioorg Med Chem, 26(8): 1453-1461 (2018) PMID: 29170028 [ doi: 10.1016/j.bmc.2017.11.009 ]
  10. Jang JP, Hwang GJ, Kwon MC, Ryoo IJ, Jang M, Takahashi S, Ko SK, Osada H, Jang JH, Ahn JS.: Pentaminomycins A and B, hydroxyarginine-containing cyclic pentapeptides from Streptomyces sp. RK88-1441.
    J Nat Prod, 81(4): 806-810 (2018) PMID: 29513529 [ doi: 10.1021/acs.jnatprod.7b00882 ]
  11. Yamagami A, Saito C, Sakuta M, Shinozaki K, Osada H, Nakano A, Asami T, Nakano T.: Brassinosteroids regulate vacuolar morphology in root meristem cells of Arabidopsis thaliana.
    Plant Signal Behav, 13(4):e1417722 (2018) PMID: 29252095 [ doi: 10.1080/15592324.2017.1417722 ]
  12. Kato N, Furutani S, Otaka J, Noguchi A, Kinugasa K, Kai K, Hayashi H, Ihara M, Takahashi S, Matsuda K, Osada H.: Biosynthesis and structure-activity relationship studies of okaramines that target insect glutamate-gated chloride channels.
    ACS Chem Biol, 13(3): 561-566 (2018) PMID: 29384650 [ doi: 10.1021/acschembio.7b00878 ]
  13. Suvarna K, Honda K, Kondoh Y, Osada H, Watanabe N.: Identification of a small-molecule ligand of β-arrestin1 as an inhibitor of stromal fibroblast cell migration accelerated by cancer cells.
    Cancer Med, 7(3): 883-893 (2018) PMID: 29380537 [ doi: 10.1002/cam4.1339 ]
  14. Robke L, Futamura Y, Konstantinidis G, Wilke J, Aono H, Mahmoud Z, Watanabe N, Wu YW, Osada H, Laraia L, Waldmann H.: Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I.
    Chem Sci, 9(11): 3014-3022 (2018) PMID: 29732085 [ doi: 10.1039/c7sc05040b ]
  15. Kaneko M, Futamura Y, Tsukuda S, Kondoh Y, Sekine T, Hirano H, Fukano K, Ohashi H, Saso W, Morishita R, Matsunaga S, Kawai F, Ryo A, Park SY, Suzuki R, Aizaki H, Ohtani N, Sureau C, Wakita T, Osada H, Watashi K.: Chemical array system, a platform to identify novel hepatitis B virus entry inhibitors targeting sodium taurocholate cotransporting polypeptide.
    Sci Rep, 8(1): 2769 (2018) PMID: 29426822 [ doi: 10.1038/s41598-018-20987-w ]
  16. Nogawa T, Kato N, Shimizu T, Okano A, Futamura Y, Takahashi S, Osada H.: Wakodecalines A and B, new decaline metabolites isolated from a fungus Pyrenochaetopsis sp. RK10-F058.
    J Antibiot, 71, 123–128 (2018) PMID: 28901329 [ doi: 10.1038/ja.2017.103 ]