Muroi M, Kawatani M, Kawamura T, Futamura Y, Osada H
Analysis of MTH1 inhibitors by ChemProteoBase, the drug-target analysis system based on proteomic profiling.
Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, Tanakaa M, Honda K, Osada H
Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival
Asian 3 round table on nucleic acids and chemical probes research hub
Sep. 22th, 2016, Fukuoka, Japan
Kawamura T, Kawatani M, Osada H
The role of the MTH1 enzyme in cancer gave rise to controversy
9th Joint Natural Products Conference 2016
Jul. 26th, 2016, Copenhagen, Denmark
Motoyama T, Tanaka Y, Osada H
Activation of fungal secondary metabolism by disturbance of the two-component signal transduction system and identification of the nectriapyrone biosynthetic gene cluster
17th Tetrahedron Symposium
Jun. 29th, 2016, Sitges, Spain
Osada H
Stereospecific ring formation in biosynthesis of specialized microbial metabolites
Kondoh Y, Honda K, Hiranuma S, Shimizu T, Osada H
Comparative chemical array screening of p38γ/δ MAPK inhibitors by focusing on a single gatekeeper residue difference between p38α/β and p38γ/δ.
May 11th, 12th, 2016, Berlin, Germany
Jonas Aretz
Upendra Rao Anumala, Paul Robin Wratil, Hannes Baukmann, Eike-Christian Wamhoff, Jonas Hanske, Hoang Giang Nguyen, Yasumitsu Kondoh, Kaori Honda, Nobumoto Watanabe, Hiroyuki Osada, Werner Reutter, Marc Nazaré, Christoph Rademacher.
The Unusual Suspects: Fragment Screening of Carbohydrate-binding Proteins.
RIKEN-Max Planck Joint Research Center for Systems Chemical Biology The 5th Symposium
Apr. 17th - 20th, 2016, Berlin, Germany
Kawamura T, Kawatani M, Kondoh Y, Muroi M, Futamura Y, Aono H, Tanaka M, Honda K, Osada H.
Identification of MTH1inhibitors by chemical arrays
Muroi M, Tanaka M, Osada H.
Expansion of ChemProteoBase for the analysis of compounds affecting cancer metabolism
Watanabe N, Osada H
14-3-3 protein-porotein interaction inhibitors identified by high throughput screening
Kondoh Y, Honda K, Hiranuma S, Shimizu T, Osada H
Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ.
Jonas Aretz, Yasumitsu Kondoh, Kaori Honda, Upendra Rao Anumala, Marc Nazaré, Nobumoto Watanabe, Hiroyuki Osada, Christoph Rademacher
Fragment arrays for early druggability assessments.
Hiroyuki Osada
Screening of small molecule compounds with activity to selectively inhibit the cancer stem cell properties.
Nobumoto Watanabe, Hiroyuki Osada
Discovery and analyses of 14-3-3 protein-protein interaction inhibitors identified by high throughput screening
Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
Novel screening approach for drug discovery from virtual mirror-image library of natural products
The 8th Korea-Japan Chemical Biology symposium
Jan. 19th, 2016, Naha, Okinawa, Japan
Yun CS, Motoyama T, Osada H.
Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzyme
Miyazawa H, Takahashi S, Shimizu T, Nogawa T, Osada H
Characterization of middle chain fatty acyl-CoA ligase responsible for the biosynthesis of 2-alkylmalonyl-CoAs for polyketide extender unit
Kato N, Nogawa T, Hirota H, Takahashi S, Jang JH, Ahn JS, Osada H
Discovery of a new enzyme involved in the stereoselective decalin formation during equisetin biosynthesis
Otaka J, Futamura Y, Osada H.
Bioactive compounds from Plant Roots
Futamura Y, Kawatani M, Aono H, Muroi M, Tanaka M, Osada H.
Phenotypic screening of small molecules targeting cancer metabolism
Katsuyama S, Sugino K, Sasazawa Y, Nakano Y, Aono H, Kawatani M, Osada H, Simizu S.
A novel osteoclastogenesis inhibitor targeting nucleoside transporters
