2016 Presentation

1st UGAS, Iwate University International Symposium 2016

Dec. 17th - 18th, 2016, Morioka, Iwate-ken, Japan
  • Shota Uesugi, Makoto Muroi, Yasumitsu Kondoh, Tetsuro Yamashita, Yoshihito Shiono, Masaru Hashimoto, Hiroyuki Osada, Ken-ichi Kimura
    Identification of the molecular targets and electrophilic properties of covalent-binding anti-cancer compounds.

The 21st JFCR-International Symposium on Cancer Chemotherapy (JFCR-ISCC)

Dec. 14th - 15th, 2016, Tokyo, Japan
  • Muroi M, Kawatani M, Kawamura T, Futamura Y, Osada H
    Analysis of MTH1 inhibitors by ChemProteoBase, the drug-target analysis system based on proteomic profiling.

International Symposium of Mycotoxicology 2016

Nov. 30th - Dec. 2nd, Tokyo, Japan
  • Toshiyoshi Yamamoto, Takahiro Kagemoto, Kurin Iimura, Yasumitsu Kondoh, Kaori Honda, Hiroyuki Osada, Shohei Sakudai.
    Effect of fluoropyrimidines on aflatoxin production.

28th EORTC-NCI-AACR symposium on molecular targets and cancer therapeutics

Nov. 30th, Munich, Germany
  • Kawamura T, Kawatani M, Muroi M, Kondoh Y, Futamura Y, Aono H, Tanakaa M, Honda K, Osada H
    Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival

Asian 3 round table on nucleic acids and chemical probes research hub

Sep. 22th, 2016, Fukuoka, Japan
  • Kawamura T, Kawatani M, Osada H
    The role of the MTH1 enzyme in cancer gave rise to controversy

9th Joint Natural Products Conference 2016

Jul. 26th, 2016, Copenhagen, Denmark
  • Motoyama T, Tanaka Y, Osada H
    Activation of fungal secondary metabolism by disturbance of the two-component signal transduction system and identification of the nectriapyrone biosynthetic gene cluster

17th Tetrahedron Symposium

Jun. 29th, 2016, Sitges, Spain
  • Osada H
    Stereospecific ring formation in biosynthesis of specialized microbial metabolites
  • Kondoh Y, Honda K, Hiranuma S, Shimizu T, Osada H
    Comparative chemical array screening of p38γ/δ MAPK inhibitors by focusing on a single gatekeeper residue difference between p38α/β and p38γ/δ.

May 11th, 12th, 2016, Berlin, Germany
  • Jonas Aretz Upendra Rao Anumala, Paul Robin Wratil, Hannes Baukmann, Eike-Christian Wamhoff, Jonas Hanske, Hoang Giang Nguyen, Yasumitsu Kondoh, Kaori Honda, Nobumoto Watanabe, Hiroyuki Osada, Werner Reutter, Marc Nazaré, Christoph Rademacher.
    The Unusual Suspects: Fragment Screening of Carbohydrate-binding Proteins.

RIKEN-Max Planck Joint Research Center for Systems Chemical Biology The 5th Symposium

Apr. 17th - 20th, 2016, Berlin, Germany
  • Kawamura T, Kawatani M, Kondoh Y, Muroi M, Futamura Y, Aono H, Tanaka M, Honda K, Osada H.
    Identification of MTH1inhibitors by chemical arrays
  • Muroi M, Tanaka M, Osada H.
    Expansion of ChemProteoBase for the analysis of compounds affecting cancer metabolism
  • Watanabe N, Osada H
    14-3-3 protein-porotein interaction inhibitors identified by high throughput screening
  • Kondoh Y, Honda K, Hiranuma S, Shimizu T, Osada H
    Comparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δ.
  • Jonas Aretz, Yasumitsu Kondoh, Kaori Honda, Upendra Rao Anumala, Marc Nazaré, Nobumoto Watanabe, Hiroyuki Osada, Christoph Rademacher
    Fragment arrays for early druggability assessments.

Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics

Feb. 16th - 20th, 2016, Maui, Hawaii, USA
  • Hiroyuki Osada
    Screening of small molecule compounds with activity to selectively inhibit the cancer stem cell properties.
  • Nobumoto Watanabe, Hiroyuki Osada
    Discovery and analyses of 14-3-3 protein-protein interaction inhibitors identified by high throughput screening
  • Taro Noguchi, Shinya Oishi, Kaori Honda, Yasumitsu Kondoh, Tamio Saito, Hiroaki Ohno, Hiroyuki Osada, Nobutaka Fujii
    Novel screening approach for drug discovery from virtual mirror-image library of natural products

The 8th Korea-Japan Chemical Biology symposium

Jan. 19th, 2016, Naha, Okinawa, Japan
  • Yun CS, Motoyama T, Osada H.
    Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzyme
  • Miyazawa H, Takahashi S, Shimizu T, Nogawa T, Osada H
    Characterization of middle chain fatty acyl-CoA ligase responsible for the biosynthesis of 2-alkylmalonyl-CoAs for polyketide extender unit
  • Kato N, Nogawa T, Hirota H, Takahashi S, Jang JH, Ahn JS, Osada H
    Discovery of a new enzyme involved in the stereoselective decalin formation during equisetin biosynthesis
  • Otaka J, Futamura Y, Osada H.
    Bioactive compounds from Plant Roots
  • Futamura Y, Kawatani M, Aono H, Muroi M, Tanaka M, Osada H.
    Phenotypic screening of small molecules targeting cancer metabolism
  • Katsuyama S, Sugino K, Sasazawa Y, Nakano Y, Aono H, Kawatani M, Osada H, Simizu S.
    A novel osteoclastogenesis inhibitor targeting nucleoside transporters