Inhibition of PDI activity.


 Almost secreted proteins will involve in disulfide bond conformation which occur intracellular leading to the activated protein. Moreover, cancer metastasis-related proteins and growth factors are secreted. Therefore, unknown cancer metastasis factors and its functional mechanisms can be evaluated with PDI inhibitor. Beside this, compounds showing the inhibitory activity can be evaluated on cancer metastatic effect with outside institution collaboration is possible.

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