NPEdia Isoxazole-4-carboxylate
Producing organism
Streptomyces sp.
Biological activity
herbicidal activity
A newly isolated strain of streptomyceste produces a phytotoxic substance. The active principle was isolated from the culture filtrate as sodium salt, C4H2NO3Na. From physico-chemical properties, the structure, isoxazole-4-carboxylic acid was deduced and confirmed by synthesis. It showed phytotoxicity agaist rice seedlings when applied on the submerged soil at the rate of 7.5 - 15 g/10a.
isolation and structural determination
  • Kobinata K, Sekido S, Uramoto M, Ubukata M, Osada H, Yamaguchi I, Isono K.
    Isoxazole-4-carboxylic acid as a metabolite of Streptomyces sp. and its herbicidal acitivity.
    Agric. Biol. Chem. 55, 1415-1416 (1991) [ doi: 10.1271/bbb1961.55.1415 ]
  • Additional information