Cytoxazone
- Structure
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- Producing organism
- Streptomyces sp.
- Biological activity
- cytokine modulator
- Abstract
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- References
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isolation and structural determination
- Kakeya H, Morishita M, Kobinata K, Osono M, Ishizuka M, Osada H.: Isolation and biological activity of a novel cytokine modulator, cytoxazone.
J Antibiot, 51(12): 1126-1128 (1998)
- Kakeya H, Morishita M, Koshino H, Morita T, Kobayashi K, Osada H.: Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp.
J Org Chem, 64(3): 1052-1053 (1999)synthesis by other group- Sakamoto Y, Shiraishi A, Seonhee J, Nakata T.
Stereoselective syntheses of cytoxazone, a novel cytokine modulator, and its stereoisomers.
Tetrahedron Lett. 40, 4203-4206 (1999) [ doi: 10.1016/S0040-4039(99)00712-1 ]- Carter PH, LaPorte JR, Scherle PA, Decicco CP.: A new synthesis of cytoxazone and its diastereomers provides key initial SAR information.
Bioorg Med Chem Lett, 13(7): 1237-1239 (2003) - Kakeya H, Morishita M, Kobinata K, Osono M, Ishizuka M, Osada H.: Isolation and biological activity of a novel cytokine modulator, cytoxazone.