Albopeptin B

Structure
NPEdia Albopeptin B
Producing organism
Streptomyces albofaciens
Biological activity
antimicrobial activity
Abstract
Antibiotics albopeptin A and B were purified from cultures of Streptomyces albofaciens by Nucleosil 5C18 HPLC. The formulas of albopeptin A and B were C39H65N11O12S and C40H65N11O12S, resp. IR spectra of albopeptins A and B. They were sol. in formic acid and trifluoroacetic acid. Albopeptins A and B showed broad antibacterial and antifungal activities. A mixt. of albopeptins A and B prevented the sheath blight disease in rice plants. Mice tolerated a mixt. of albopeptins A and B at 600 mg/kg.
References
isolation and structural determination
  • Isono K, Kobinata K, Oikawa H, Kusakabe H, Uramoto M, Ko K, Misato T, Tai SW, Ni CT, Shen YC.
    New antibiotics, albopeptins A and B.
    Agric. Biol. Chem. 50, 2163-2165 (1986) [ doi: 10.1271/bbb1961.50.2163 ]
  • synthesis by other group
  • Oikawa H, Fukushi E, Nishitoba T, Ichihara A, Kobinata K, Isono K.
    The structures of peptide antibiotics, albopeptin B and its analog.
    Tennen Yuki Kagobutsu Toronkai Koen Yoshishu 34, 574-581 (1992) [ J-GLOBAL ID: 200902051683752890 ]
  • Additional information