FSL0837
- Structure
- InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20?/t21?,23-,24-,25-,29+,34+,35-,39+,43+/m1/s1
- InChIKey=JQXXHWHPUNPDRT-OUBGVEFFSA-N
- Synonyms
-
- 13292-46-1
- Fifadin
- Rifampicin
- Rifampin
- Rimactane
- Origin
- Chemically synthesized
- Biological activities
- Inhibits RNA synthesis by blocking transcription in bacteria
- Therapeutic
-
Antibacterial
- Target
-
RNA polymerase
Serum albumin
- Assay information
-
Inhibitor of the growth of Mycobacterium tuberculosis (0.005-0.02 μg/ml)
Blocking activity against Vaccinia virus particle formation
Blocking activity against uracil uptake (1-5 μg/ml or more)
MIC [μg/ml]: S. aureus (0.008-0.016), S. epidermidis (0.004-0.016), E. coli (8-16), P. aeruginosa (16-32)