FSL0373
- Structure
- InChI=1S/C30H46O16S2.2K/c1-14(2)9-22(32)44-25-24(46-48(39,40)41)23(45-47(36,37)38)20(13-31)43-28(25)42-17-10-18(27(34)35)19-7-8-30-11-16(15(3)26(30)33)5-6-21(30)29(19,4)12-17;;/h14,16-21,23-26,28,31,33H,3,5-13H2,1-2,4H3,(H,34,35)(H,36,37,38)(H,39,40,41);;/q;2*+1/p-2/t16?,17-,18-,19-,20?,21+,23?,24?,25?,26+,28?,29-,30-;;/m1../s1
- InChIKey=IUCNQFHEWLYECJ-UAPRPQGYSA-L
- Synonyms
-
- 102130-43-8
- Atractyloside potassium salt
- Origin
- Atractylis gummifera
- Biological activities
- Inhibition of oxidative phosphorylation
- Therapeutic
-
Herbal poisoning
- Target
-
Adenine nucleotide translocase
- Assay information
-
Selective inhibition of adenine nucleotide translocase (Kd = 50 nM) and induction of permeability transition pore opening