FSL0424
- Structure
- InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23)
- InChIKey=MAEIEVLCKWDQJH-UHFFFAOYSA-N
- Synonyms
-
- Origin
- Chemically synthesized
- Biological activities
- Sodium potassium chloride symporter Inhibitors
- Therapeutic
-
Diuretic (loop diuretic)
Heart failure
- Target
-
NKCC1 cation-chloride co-transporter
- Assay information
-
Na-K-Cl cotransporter (NKCC1) decreases internal chloride concentration in neurons (Affinity: ca 0.5 μM)