FSL0560

Structure

• InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;
• InChIKey=RXKMOPXNWTYEHI-RDRKJGRWSA-N

Synonyms

• 30484-77-6
• Flunarizine hydrochloride

Origin

Chemically synthesized

Biological activities

Blocking Ca²⁺ entry
Blocking histamine H1

Therapeutic

Anticonvulsant

Target

Voltage-dependent T-type calcium channel subunit α-1G,1H, 1I.
Histamine H1 receptor
Calmodulin

Assay information

Neuronal T-type Ca channel (K_d [nM]): α1G (530), α1H (3552), α1I (837)
Histamine H1 blocking activity