FSL0312
- Structure
- InChI=1S/C18H28N2O4.ClH/c1-5-6-18(23)20-14-7-8-17(16(9-14)13(4)21)24-11-15(22)10-19-12(2)3;/h7-9,12,15,19,22H,5-6,10-11H2,1-4H3,(H,20,23);1H
- InChIKey=KTUFKADDDORSSI-UHFFFAOYSA-N
- Synonyms
-
- 34381-68-5
- Acebutolol hydrochloride
- Origin
- Chemically synthesized
- Biological activities
- β-adrenoreceptor antagonist
Mild intrinsic sympathomimetic activity
- Therapeutic
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Antiangina
Antiarrhythmic (class II)
Antihypertensive
- Target
-
Selective β1-adrenergic receptors
- Assay information
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Effects on the activation of Adenylate cyclase from heart and liver induced by 1-isoproterenol (IC50 [μM]): Heart (9.0), Liver (838.9)
Isoprenaline-induced tachycardia and diastolic hypotension antagonize avtivity