FSL0888

Structure

• InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
• InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N

Synonyms

• 127-79-7
• Sulfamerazine

Origin

Chemically synthesized

Biological activities

Inhibition of folic acid synthesis in bacteria

Therapeutic

Antibacterial

Target

Dihydropteroate synthase (DHPS)

Assay information

Competitive inhibition of DHPS from P. carinii (IC₅₀ = 0.078 mM)