FSL0817

Structure

• InChI=1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H
• InChIKey=ZFSPFXJSEHCTTR-UHFFFAOYSA-N

Synonyms

• 1508-76-5
• Procyclidine hydrochloride

Origin

Chemically synthesized

Biological activities

An anticholinergic effect (muscarinic antagonist)

Therapeutic

Anticholinergic
Antiparkinsonian

Target

Muscarinic acetylcholine receptor M₁, M₂, and M₄

Assay information

(R)-Procyclidine showed a higher affinity for human neuroblastoma NB-OK 1 muscarinic M₁ (pK_i 8.4) and rat striatum muscarinic M₄ (pK_i 8.1) receptors, as compared to rat cardiac M₂ recep
(S)-Procyclidine had a lower affinity than (R)-procyclidine