FSL0809
- Structure
- InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2
- InChIKey=FSVJFNAIGNNGKK-UHFFFAOYSA-N
- Synonyms
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- Origin
- Chemically synthesized
- Biological activities
- Increases the permeability of the membranes towards calcium ions
- Therapeutic
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Anthelmintic
Antihydatidosis
Broad spectrum
- Target
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Schistosome Calcium (Ca2+) Channel
- Assay information
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Inhibition of nucleoside uptake in living worms and may be specifically related to adenosine uptake or signaling (mouse LD50 = 376mg/kg)
Treatment of children (n = 592) infected with Schistosoma haematobium in a single dose of praziquantel (40 mg/kg), showing high activity (cure rate >gt; 83% and egg reduction rate >gt; 98%)