NPEdia

FSL0809

Structure
FSL0809
Synonyms
Origin
Chemically synthesized
Biological activities
Increases the permeability of the membranes towards calcium ions
Therapeutic
Anthelmintic
Antihydatidosis
Broad spectrum
Target
Schistosome Calcium (Ca2+) Channel
Assay information
Inhibition of nucleoside uptake in living worms and may be specifically related to adenosine uptake or signaling (mouse LD50 = 376mg/kg)
Treatment of children (n = 592) infected with Schistosoma haematobium in a single dose of praziquantel (40 mg/kg), showing high activity (cure rate >gt; 83% and egg reduction rate >gt; 98%)