FSL0580

Structure

• InChI=1S/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)
• InChIKey=HEMJJKBWTPKOJG-UHFFFAOYSA-N

Synonyms

• 25812-30-0
• Gemfibrozil

Origin

Chemically synthesized

Biological activities

PPAR activation (up-regulation of tripeptidyl-peptidase)

Therapeutic

Hyperlipidemia
(lipid-lowering drug)

Target

Peroxisome proliferator-activated receptor α (PPARα)

Assay information

Up-regulates tripeptidylpeptidase 1 in brain cells via PPARα (effective dose: ca 10 μM)
Increases myelin genes in human oligodendrocytes via PPARβ (effective dose: ca 10 μM)