FSL0647
- Structure
- InChI=1S/C26H30O8/c1-22(2)15-9-16(27)24(4)14(25(15)12-31-18(28)10-17(25)33-22)5-7-23(3)19(13-6-8-30-11-13)32-21(29)20-26(23,24)34-20/h6,8,11,14-15,17,19-20H,5,7,9-10,12H2,1-4H3/t14-,15-,17-,19-,20?,23-,24-,25+,26+/m0/s1
- InChIKey=KBDSLGBFQAGHBE-QDTQPDKMSA-N
- Synonyms
-
- 1180-71-8
- Limonin, from Grapefruit
- Origin
- Citrus
- Biological activities
- Inhibition of HIV-1replication
- Therapeutic
-
Anticancer
Antiviral
- Target
-
Unknown
- Assay information
-
Inhibition of HIV-1 replication (human peripheral blood mononuclear cells and on monocytes/macrophages, EC50: ca. 60 μM)
Growth inhibition against some cancer cells ( IC50: MCF7, 13.48 μg/ml; SW480, 54.74 μM)