FSL0281

Structure

• InChI=1S/C8H16N2O2S2/c1-5-11-6-2-9(1)13-14-10-3-7-12-8-4-10/h1-8H2
• InChIKey=HLBZWYXLQJQBKU-UHFFFAOYSA-N

Synonyms

• 103-34-4
• 4,4'-Dithiodimorpholine

Origin

Chemically synthesized

Biological activities

Inhibition of cell viability and induction for apotosis.

Therapeutic

Anticancer
Antiviral

Target

HPV E6 protein

Assay information

Inhibition of the growth of the tumorigenic HPV (human papillomavirus) cell lines SiHa, CaSki, and HeLa at concentrations of 50 μM
Inhibition of cell vibility of tumor and non-tumor cells: PHFK (LD₅₀: 25.1, 25.8, 24.0 μM (24, 48, 72h)), C33A (LD₅₀: 26.4, 28.9, 22.9 μM (24, 48, 72h)), SiHa (LD₅₀: 42.3, 35.1, 31.6 μM (24, 48, 72h