Assay List
Assays using mammal cell lines.
- Assays for cell growth and differentiation.
(1) Screening of cell cycle inhibitors by a bioassay using a mouse cdc2 mutant cell line, tsFT210. ⇒Details
(2) Screening of inhibitors of mitogenic activity of EGF. ⇒Details
- Assays for cell differentiation.
(1) Screening for inducer of cell differentiation using HL60 cells. ⇒Details
(2) Screening for neutrophic factors and inhibitors of NGF using PC-12 or SH-SY5Y cells. ⇒Details
(3) Screening of compounds which repress NGF-induced differentiation of PC-12 cells. ⇒Details
(4) Screening for inducer of K-562 cell differentiation. ⇒Details
(5) Screening for inhibitors of bone formation using C3H10T1/2 cells, and MC3T3E1 cells. ⇒Details
- Assays for cell morphological transformation.
(1) Screening for compounds with morphological reversion activity on transformed cells. ⇒Details
(2) The bleb forming assay for the activators and inhibitors of PKC. ⇒Details
Assays using microbial cells.
- Molecular targeting assay
(1) Screening for HIV-1 Vpr inhibitors. ⇒Details
(2) Screening for p38 MAP kinase inhibitors. ⇒Details
- Assays using morphological response of microbial cell.
(1) Screening of antifungal agents through the morphological changes in rice blast fungi.⇒Details
In vitro assays.
- Assays for protein functions.
(1) Screening for inhibitors or activators of MAP kinases. ⇒Details
(2) Screening for heparanase inhibitors. ⇒Details
(3) Screening for inhibitors of PDI. ⇒Details
(4) Screening for tyrosine phosphatase inhibitors. ⇒Details
- Assays for protein-protein interactions.
(1) Screening for PBD-dependent binding inhibitors. ⇒Details
- Assays for interaction mechanisms between proteins and small molecules.
(1) SPR imaging of photo-cross-linked small molecule microarrays on gold. ⇒Details
(2) Identification of target proteins using small molecule affinity matrix. ⇒Details
Omics assays.
- Genome-wide screening by chemical array technology. ⇒Details
- Drug target analysis based on proteomic analysis by 2D-DIGE. (ChemProteoBase) ⇒Details