Original Articles 2012
- Motoyama T, Hayashi T, Hirota H, Ueki M, Osada H.:
Terpendole E, a Kinesin Eg5 Inhibitor, Is a Key Biosynthetic Intermediate of Indole-Diterpenes in the Producing Fungus Chaunopycnis alba,
Chemistry & Biology, 19 (12): 1611-1619, (2012)
[ doi: 10.1016/j.chembiol.2012.10.010 ]
- Futamura Y, Kawatani M, Kazami S, Tanaka K, Muroi M, Shimizu T, Tomita K, Watanabe N, Osada H.:
Morphobase, an Encyclopedic Cell Morphology Database, and Its Use for Drug Target Identification,
Chemistry & Biology, 19 (12): 1620-1630, (2012)
[ doi: 10.1016/j.chembiol.2012.10.014 ]
- Ishii K, Saito T, Osada H, Taniguchi N, Suzuki T.: Identification of compounds that augment the lectin-sensitivity of Chinese Hamster Ovary cells.
Biochem Biophys Res Commun, 423 (2): 429-435 (2012) [ doi: 10.1016/j.bbrc.2012.05.152 ]
- Noutoshi Y, Ikeda M, Saito T, Osada H, Shirasu K.: Sulfonamides identified as plant immune-priming compounds in high-throughput chemical screening increase disease resistance in Arabidopsis thaliana.
Front Plant Sci, 3 245 (2012) [ doi: 10.3389/fpls.2012.00245 ]
- Asami Y, Jang JH, Oh H, Sohn JH, Kim JW, Moon DO, Kwon O, Kawatani M, Osada H, Kim BY, Ahn JS.: Violaceols function as actin inhibitors inducing cell shape elongation in fibroblast cells.
Biosci Biotechnol Biochem, 76 (8): 1431-1437 (2012) [ doi: 10.1271/bbb.120074 ]
- Tanaka M, Miyazawa K, Tabuchi M, Yabumoto T, Kadota M, Yoshizako M, Yamane C, Kawatani M, Osada H, Maeda H, Goto S.:
Effect of reveromycin A on experimental tooth movement in OPG-/- mice.
J Dent Res, 91 (8): 771-776 (2012) [ doi: 10.1177/0022034512451026 ]
- Osada H, Nogawa T.:
Systematic isolation of microbial metabolites for natural products depository (NPDepo)
Pure Appl Chem., 84(6): 1407-1420 (2012) [ doi: 10.1351/PAC-CON-11-08-11 ]
- Asami Y, Jang JH, Soung NK, He L, Moon DO, Kim JW, Oh H, Muroi M, Osada H, Kim BY, Ahn JS.: Protuboxepin A, a marine fungal metabolite, inducing metaphase arrest and chromosomal misalignment in tumor cells.
Bioorg Med Chem, 20(12): 3799-3806 (2012) [ doi: 10.1016/j.bmc.2012.04.039 ]
- Bürger M, Zimmermann TJ, Kondoh Y, Stege P, Watanabe N, Osada H, Waldmann H, Vetter IR.:
Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases.
J Lipid Res. 53: 43-50 (2012) [ doi: 10.1194/jlr.M019851 ]
- Hullin-Matsuda F, Tomishige N, Sakai S, Ishitsuka R, Ishii K, Makino A, Greimel P, Abe M, Laviad EL, Lagarde M, Vidal H, Saito T, Osada H, Hanada K, Futerman AH, Kobayashi T.:
Limonoid Compounds Inhibit Sphingomyelin Biosynthesis by Preventing CERT-dependent Extraction of Ceramides from the Endoplasmic Reticulum.
J Biol Chem, (2012) [ doi: 10.1074/jbc.M112.344432 ]
- Khan MM, Simizu S, Suzuki T, Masuda A, Kawatani M, Muroi M, Dohmae N, Osada H.:
Protein disulfide isomerase-mediated disulfide bonds regulate the gelatinolytic activity and secretion of matrix metalloproteinase-9.
Exp Cell Res., 18(8): 904-914 (2012) [ doi: 10.1016/j.yexcr.2012.02.021 ]
- Nogawa T, Takahashi S, Okano A, Kawatani M, Uramoto M, Saito T, Osada H.:
Spirotoamides A and B, novel 6,6-spiroacetal polyketides isolated from a microbial metabolite fraction library.
J Antibiot, 65(3): 123-128 (2012) [ doi: 10.1038/ja.2011.121 ]
- Sasazawa Y, Kanagaki S, Tashiro E, Nogawa T, Muroi M, Kondoh Y, Osada H, Imoto M.:
Xanthohumol Impairs Autophagosome Maturation through Direct Inhibition of Valosin-Containing Protein.
ACS Chem Biol, 7(5): 892-900. [ doi: 10.1021/cb200492h ]
- Tsuchiya A, Hirai G, Koyama Y, Oonuma K, Otani Y, Osada H, Sodeoka M.:
Dual-Specificity Phosphatase CDC25A/B Inhibitor Identified from a Focused Library with Nonelectrophilic Core Structure.
ACS Med Chem Lett, 3(4): 294-298 (2012) [ doi: 10.1021/ml2002778 ]
- Tajul MI, Motoyama T, Hatanaka A,Sariah M, Osada H :
Green-odour compounds have antifungal activity against the rice blast fungus Magnaporthe oryzae.
Eur J Plant Pathol., 132(1): 91-100 (2012) [ doi: 10.1007/s10658-011-9851-x ]