NPEdia

NPL70571-01

Structure
NPL70571-01
Synonyms
Origin
Colchicum autumnale
Biological activities
Inhibition of microtubule polymerization
Therapeutic
Anticancer
Target
Tubulin beta-1 chain
Assay information
Inhibition of microtubule polymerization (IC50 = 3.2 μM)
Growth inhibition against cancer cells (MCF7; 13 nM)
Inhibition of mitosis (>gt; 50 nM)
Inhibition of human trophoblast differentiation (2.5 - 250 μM)
References