NPEdia

FSL0784

Structure
FSL0784
Synonyms
Origin
Biological activities
A noncompetitive antagonist at GABA receptors
Therapeutic
CNS stimulant
Target
GABA-A receptors
Assay information
Inhibition of tiagabine-elicited depolarizations (100 μM) as the GABAa receptor antagonist
A potent antagonist of GABA receptors (IC50: 237 nM) at synapses in central nervous system
Inhibition of 35S-t-buthylbicyclophosphoro-thionate binding to the Cl-channel (IC50: 1.7 μM)
References