NPEdia

FSL0707

Structure
FSL0707
Synonyms
Origin
Chemically synthesized
Biological activities
Suppression of the opiate overdose effects
Therapeutic
Antinarcotic
Target
Opioid receptors
Cyclic AMP-responsive element-binding protein 1
Assay information
A narcotic atagonist to treat narcotic overdose
Binding to all of three opioid receptors (μ, κ and δ)
Strongest binding is to the μ-receptor (Ki for μ =1.8 nM, for κ = 17.2 nM, for δ = 27.0 nM)
References